Journal article
Comparison of predictive performance of renal function estimation equations for all-cause and cardiovascular mortality in an elderly hypertensive population
EK Chowdhury, RG Langham, A Owen, H Krum, LMH Wing, MR Nelson, CM Reid
American Journal of Hypertension | OXFORD UNIV PRESS | Published : 2015
DOI: 10.1093/ajh/hpu160
Abstract
Background The Modifications of Diet in Renal Disease (MDRD) and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) are 2 equations commonly used to estimate glomerular filtration rate (eGFR). The predictive performance offered by these equations, particularly in relation to clinical outcomes in elderly hypertensive patients, is not clear. methods The Second Australian National Blood Pressure Study cohort was used to investigate the predictive performance of these 2 equations for longterm outcomes (median 10.8 years) in elderly treated hypertensive patients. Both equations were used to calculate eGFR in 6,083 patients aged .65 years and classified as having chronic kidney disease (C..
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Awarded by Merck Sharp and Dohme
Funding Acknowledgements
The ANBP2 was supported by the Australian Commonwealth Department of Health and Aging; the National Health and Medical Research Council (NHMRC) of Australia (grant 546272); and Merck Sharp & Dohme (Australia) Pty Ltd. The long-term ANBP2 cohort follow-up study was supported by a NHMRC Program grant (546272) awarded to C.M.R., who is supported by a NHMRC Research Fellowship (1045862). We are indebted to the participants, family practitioners, study staffs, data management centers, and ANBP2 Management Committee. The Management Committee consists of the following members: Lindon M.H. Wing (chair), Christopher M. Reid, Lawrence J. Beilin, Mark A. Brown, Garry L.R. Jennings, Collin I. Johnston, John J. McNeil, John E. Marley, Trefor O. Morgan, Philip Ryan, John Shaw (deceased), Malcolm J. West, and Graham J. MacDonald.